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| What is CoQ10? |
CoQ10 is a powerful, fat-soluble, vitamin-like
substance found naturally with the body. It is an essential
component of the cellular machinery used to produce ATP,
which provides the energy for all vital cellular function.
CoQ10 is found in every cell in the body, with especially
high concentrations in the heart, which requires high
levels of energy for normal operation. It is one of the
most powerful biosynthesized, lipid-soluble antioxidants
known. In
its pure manufactured form, CoQ10 is a yellow-orange, tasteless,
crystalline powder.
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| Why is CoQ10 Important? |
CoQ10 has two pivotal roles in our
bodies: bioenergetics
(energy metabolism) and lipid-soluble antioxidant protection.
All of our metabolic systems require constant energy input
in order to function properly. This energy is generated
through cellular respiration in the mitochondria, the powerhouse
of the cell. CoQ10 is a critical component of the
electron transfer chain in mitochondrial respiration. CoQ10
is found in the highest concentrations in organs that have
the highest metabolic energy requirements, such as the
heart, kidney, liver and skeletal muscle.
It is important to note that the levels of CoQ10 decrease
as we age and that this decrease in CoQ10 is associated
with the aging process and many age-related conditions. Supplementation with CoQ10 replenishes
the diminished levels of CoQ10, fostering a protective
defense against oxidative stress and age-related disease.
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| Does Everyone Need A CoQ10 Supplement? |
Not everyone needs
to take a CoQ10 supplement. In
young and healthy individuals, the body produces adequate
levels of CoQ10. However, as people age, the ability of
the body to produce and metabolize CoQ10 declines. This
can be due to a number of reasons including insufficient
dietary intake, disease, increased metabolic demand or
oxidative stress. Some reports indicate the decline in
CoQ10 becomes apparent around 40 years old, with others
reporting a decline as early as age 20. Because decreases
in CoQ10 are associated with the aging process and many
age-related diseases, many people could potentially benefit
from supplementing CoQ10. People who suffer from risk factors
of age-related diseases or conditions should raise their
CoQ10 levels as soon as possible (see
clinical testing); and those who wish to boost energy
levels and improve overall health also should consider
daily supplements of CoQ10.
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| Are There Any Side Effects From Taking CoQ10? |
CoQ10 supplements have been consumed by
millions of people for more than 30 years without serious
adverse effects. That
is because CoQ10 exists naturally in the human body. No adverse effect causally related to CoQ10 consumption by humans has been identified, and thus a NOAEL (or LOAEL) cannot be identified, and a UL cannot be derived. The dosages used in clinical trials are evaluated for adequacy to establish with confidence a lack of adverse effect at that level of CoQ10 intake. Therefore, the clinical trial data were evaluated to identify an OSL (termed HOI in the FAO/WHO report). Congestive heart failure patients who have shown improved
heart function after supplemental CoQ10 may regress to
their baseline function if their supplemental CoQ10 is
discontinued and should consult a physician before taking
any supplements including CoQ10. (See
clinical testing).
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| Can I get CoQ10 through the foods I eat?
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CoQ10 is found in many foods, but at very
low concentrations. It
would be extremely difficult to acquire a reasonable dose
of CoQ10 strictly through the typical Western diet. One
would have to consume approximately three pounds of sardines
or 15 pounds of broccoli a day to provide the minimal suggested
supplementation levels.
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What Forms Of CoQ10 Supplements Are Available And
What Is The Recommended Daily Dosage? |
CoQ10 is available in capsules,
tablets and oil-based softgel form. CoQ10 is typically
found in strengths ranging from 30-300 mg. According
to most medical advice, adult levels of CoQ10 supplementation
are in the 30-100 mg range daily*. Those taking CoQ10
to address a specific health problem may take higher
doses, but should consult a doctor to determine the recommended
level for their individual needs. KanekaQ10
has been tested in dozens of safety studies up to clinical
doses of 3,000 mgs per day, showing no adverse effects. For
optimum absorption of CoQ10, it is recommended that CoQ10
be taken with meals (see
clinical testing).
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Is CoQ10 Available In Products Other Than Supplements?
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Yes,
in addition to being available as a dietary supplement
in capsules and softgels, CoQ10 can be found in a growing
number of consumer products, including oral care and skin
products as well as functional foods and beverages. Amounts
of CoQ10 vary by product, as does bio-availability of the
CoQ10 in each product.
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Where Can I Buy CoQ10 Supplements And Other
Products Containing CoQ10?
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CoQ10 is available in health food stores and pharmacies,
in leading drug and department stores, in mass merchandising
stores and supermarkets across the country, and by direct
mail from manufacturers.
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